if you are thinkning about doin that then you would be completely building your block. micropolished crank, forged pistons and rods, and a sleeved block with this you should have no problem throwing whatever at your engine, boost and spray your engine could hold up but everything else will prolly go to shit.
sometimes its not just just putting every performace part on you car just cause you can. use the parts that work together well.
If nitrous and boost is what you want then do it! i know a guy running 50 PSI and a 75 shot all the way. the reason he can do that is because he has it tuned perfectly and changes the settings based even on the temp and such. he has a laptop constantly making adjustments. its pretty sweet