the twin turbo set up is possible, but costly and our engines aren't built for monster power.
the turbo+supercharger set up is good in theory but impractical in real life. There was a CRX guy that had a turbo+supercharger set up but the car never ran, too much shit to fuck up with.
You shouldn't turbo your car unless you got time, money and commitment to really work on your car, cause force inductioning a NA car is a lot of work to keep up if you run it a lot.
IMO the turbo is better, you get more high end gains, which is where you need it cause when you are racing you never go in the low rpm range its always in the high rpm range, well atleast thats how its supposed to be. And its easier to gain extra hp with a boost controller as with a sc you need to get a new pulley just to change the boost setting.